SCHEMBL28237494

SCHEMBL28237494

CC(Cl)C(C)n1c(N)nc2nc[nH]c2c1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.42
PNP P00491 1/20 0.41
GDA Q9Y2T3 2/20 0.41
PDPK1 O15530 1/20 0.41
CDK2 P24941 6/20 0.40
CDK1 P06493 5/20 0.40
CCNB1 P14635 5/20 0.40
CCNA2 P20248 5/20 0.40
CCNA1 P78396 5/20 0.40
ADORA2B P29275 2/20 0.40
MGMT P16455 1/20 0.36
CYP1A2 P05177 1/20 0.36
MAP3K5 Q99683 1/20 0.36
ADORA2A P29274 1/20 0.36
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
DRD3 P35462 1/20 0.35
PI4KA P42356 1/20 0.35
XDH P47989 1/20 0.35
LRRK2 Q5S007 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL441798 0.89 DPP4 (0.44) DPP4PNPGDAPDPK1CDK2
SCHEMBL2385930 0.85 ADORA2B (0.50) DPP4PNPGDAPDPK1CDK2
SCHEMBL9806974 0.84 PNP (0.44) DPP4PNPGDAPDPK1CDK2
SCHEMBL6751932 0.83 PNP (0.43) DPP4PNPGDAPDPK1CDK2
SCHEMBL29174358 0.80 PNP (0.45) DPP4PNPGDAPDPK1CDK2
SCHEMBL6266585 0.78 CDK1 (0.40) PNPGDAPDPK1CDK2CDK1
SCHEMBL15743135 0.78 CDK1 (0.42) DPP4PNPGDAPDPK1CDK2
SCHEMBL6952184 0.77 SLC2A1 (0.41) PNPGDAPDPK1CDK2CDK1
SCHEMBL28460015 0.76 CDK2 (0.38) PNPGDAPDPK1CDK2CDK1
SCHEMBL27617652 0.75 PNP (0.44) PNPCDK2CDK1CCNB1CCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108484604-A Azo fragrance nitrogen oxides-chlorethylnitrosourea coupling molecule of target tumor hypoxemia and its preparation method and application 北京工业大学 2018-09-04 CN disclosed