Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.42 |
| ▸ | PPARD | Q03181 | 8/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | GCGR | P47871 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821435 | 0.90 | PPARA (0.53) | PPARAPPARDPPARG | |
| SCHEMBL2818531 | 0.88 | PPARD (0.41) | PPARAPPARDPPARGGCGRGPR119 | |
| SCHEMBL2822928 | 0.78 | PPARA (0.52) | PPARAPPARDPPARGGCGR | |
| SCHEMBL2821447 | 0.73 | GCGR (0.36) | GCGRGPR119NPC1RAB9A | |
| SCHEMBL1549155 | 0.69 | CYP4F2 (0.47) | PPARAPPARGNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12151282 | 0.68 | DRD2 (0.47) | PPARAPPARDPPARG | |
| SCHEMBL2823052 | 0.67 | PPARA (0.50) | PPARAPPARDPPARG | |
| SCHEMBL2819648 | 0.67 | HDAC1 (0.44) | PPARAPPARD | |
| SCHEMBL6583498 | 0.67 | PPARA (0.59) | PPARAPPARDPPARGNPC1 | |
| SCHEMBL4575333 | 0.67 | PPARA (0.48) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | PPARA, PPARD, PPARG | PPARA 1/4885PPARD 2/4885PPARG 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.