Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30177201 | 0.90 | IRAK4 (0.43) | MPOHPGDIRAK4KDM4ERAB9A | |
| SCHEMBL10123647 | 0.80 | SLC6A2 (0.44) | HPGDKDM4ERAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL13607537 | 0.80 | IRAK4 (0.39) | MPOHPGDIRAK4KDM4ERAB9A | |
| SCHEMBL30995500 | 0.79 | MAP4K4 (0.43) | IRAK4KDM4ERAB9AALDH1A1TSHR | |
| SCHEMBL14909598 | 0.79 | KDM4E (0.58) | MPOHPGDIRAK4KDM4ERAB9A | |
| SCHEMBL25219391 | 0.79 | NFATC1 (0.42) | MPOIRAK4ALDH1A1HSD17B10 | |
| SCHEMBL28505047 | 0.79 | IRAK4 (0.32) | IRAK4KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL13607538 | 0.79 | IRAK4 (0.41) | HPGDIRAK4KDM4ERAB9AALDH1A1 | |
| SCHEMBL19128033 | 0.78 | IRAK4 (0.36) | MPOHPGDIRAK4KDM4EALDH1A1 | |
| SCHEMBL24338409 | 0.78 | IRAK4 (0.43) | MPOIRAK4KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473471-A | Substituted thiourocystine derivatives as androgen receptor antagonists | 詹森药业有限公司 | 2018-08-31 | — | — | CN | claimed |
| CN-108473471-A | Substituted thiourocystine derivatives as androgen receptor antagonists | 詹森药业有限公司 | 2018-08-31 | — | — | CN | disclosed |