Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 6/20 | 0.42 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28238879 | 0.84 | HPGD (0.51) | RIPK1HPGDMGLL | |
| SCHEMBL19146343 | 0.81 | PIK3CA (0.45) | PIK3CARIPK1LRRK2HPGDJAK2 | |
| SCHEMBL19126423 | 0.81 | PIK3CA (0.45) | PIK3CALRRK2HPGDALDH1A1 | |
| SCHEMBL19126328 | 0.81 | PIK3CA (0.45) | PIK3CALRRK2MGLLHTR2BALDH1A1 | |
| SCHEMBL19126428 | 0.81 | PIK3CA (0.45) | PIK3CALRRK2HPGDHTR2B | |
| SCHEMBL19126514 | 0.81 | PIK3CA (0.45) | PIK3CAHPGDJAK2ALDH1A1 | |
| SCHEMBL28238897 | 0.81 | HPGD (0.48) | HPGDMGLLALDH1A1 | |
| SCHEMBL19126670 | 0.81 | ALK (0.46) | PIK3CALRRK2HTR2B | |
| SCHEMBL19144550 | 0.80 | POLB (0.50) | PIK3CARIPK1HPGDMGLLHTR2B | |
| SCHEMBL19127065 | 0.79 | ALDH1A1 (0.46) | PIK3CAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473485-A | QUINOLIN-2-ONE DERIVATIVES | 默克专利股份公司 | 2018-08-31 | — | — | CN | claimed |
| CN-108473485-A | QUINOLIN-2-ONE DERIVATIVES | 默克专利股份公司 | 2018-08-31 | — | — | CN | disclosed |