Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.49 |
| ▸ | TUBB | P07437 | 3/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122555 | 1.00 | MEN1 (0.52) | MEN1MAPTKMT2AGAAALDH1A1 | |
| SCHEMBL8130453 | 0.87 | MAPT (0.53) | MEN1MAPTKMT2AGAAALDH1A1 | |
| SCHEMBL8124060 | 0.86 | MEN1 (0.52) | MEN1MAPTKMT2AGAAALDH1A1 | |
| SCHEMBL8135923 | 0.86 | MAPT (0.52) | MEN1MAPTKMT2AGAAALDH1A1 | |
| SCHEMBL28239032 | 0.86 | MAPT (0.52) | MEN1MAPTKMT2AGAAALDH1A1 | |
| SCHEMBL8116052 | 0.86 | MAPT (0.52) | MEN1MAPTKMT2AGAAALDH1A1 | |
| SCHEMBL8132637 | 0.85 | MEN1 (0.68) | MEN1MAPTKMT2AGAAALDH1A1 | |
| SCHEMBL28239033 | 0.85 | MAPT (0.52) | MEN1MAPTKMT2AGAAALDH1A1 | |
| SCHEMBL8122814 | 0.85 | GAA (0.49) | MEN1MAPTKMT2AGAAALDH1A1 | |
| SCHEMBL829253 | 0.84 | TUBB1 (0.68) | MEN1MAPTKMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503561-A | The preparation of the combretastatin A4 analogs of cyano-containing and halogen and purposes | 延边大学 | 2018-09-07 | — | — | CN | disclosed |