Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | KIF20A | O95235 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8134746 | 0.85 | MAPT (0.53) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8122555 | 0.85 | MEN1 (0.52) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL28238026 | 0.85 | MEN1 (0.52) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8132637 | 0.85 | MEN1 (0.68) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL28862938 | 0.84 | MAPT (0.52) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL8118305 | 0.84 | KIF20A (0.54) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4998911 | 0.83 | RECQL (0.55) | MAPTMEN1KMT2AALDH1A1PTGS1 | |
| SCHEMBL4998908 | 0.83 | RECQL (0.55) | MAPTMEN1KMT2AALDH1A1PTGS1 | |
| SCHEMBL11822393 | 0.82 | MEN1 (0.67) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL11822409 | 0.82 | MEN1 (0.67) | MAPTMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503561-A | The preparation of the combretastatin A4 analogs of cyano-containing and halogen and purposes | 延边大学 | 2018-09-07 | — | — | CN | disclosed |