SCHEMBL28238546

SCHEMBL28238546

CCC(c1ccccc1)N(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
TRPM8 Q7Z2W7 1/20 0.42
TP53 P04637 2/20 0.41
MAPT P10636 2/20 0.41
HTR2A P28223 3/20 0.41
HRH1 P35367 3/20 0.41
TDP1 Q9NUW8 1/20 0.40
AOC3 Q16853 1/20 0.40
SIGMAR1 Q99720 1/20 0.38
MIF P14174 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
GLA P06280 1/20 0.38
HKDC1 Q2TB90 1/20 0.37
TRPA1 O75762 1/20 0.37
TAAR1 Q96RJ0 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11141579 0.81 LMNA (0.47) LMNATRPM8TP53MAPTHTR2A
SCHEMBL29059910 0.80 HTR2A (0.45) LMNATRPM8HTR2AHRH1TDP1
SCHEMBL119104 0.79 HTR2A (0.48) LMNATRPM8HTR2AHRH1TDP1
SCHEMBL171013 0.79 HTR2A (0.48) LMNATRPM8HTR2AHRH1TDP1
SCHEMBL8926699 0.79 HTR2A (0.48) LMNATRPM8HTR2AHRH1TDP1
SCHEMBL8576434 0.77 LMNA (0.52) LMNATRPM8HTR2AHRH1TDP1
Hydrochloric Acid SCHEMBL14762879 0.77 TDP1 (0.50) LMNATRPM8MAPTHTR2AHRH1
Iodide SCHEMBL10962372 0.77 HTR2A (0.46) LMNATRPM8HTR2AHRH1TDP1
SCHEMBL1031859 0.77 LMNA (0.52) LMNATRPM8HTR2AHRH1TDP1
Hydrochloric Acid SCHEMBL18378384 0.77 TDP1 (0.50) LMNATRPM8MAPTHTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108276625-B A kind of safety shoe resistant to high temperatures and its manufacturing method 温州鑫彩鸿安防科技有限公司 2019-11-22 CN claimed
CN-106832464-A A kind of high temperature resistant low performance loss cleaned air tube material and preparation method thereof 安徽中鼎密封件股份有限公司 2017-06-13 CN claimed
CN-106281580-A Preparation method of soot ashless dispersant 中国石油天然气股份有限公司 2017-01-04 CN claimed
CN-110424212-A A kind of corrosion resistant plastic cement race track and its processing method ANHUI LVGU NEW MAT CO LTD 2019-11-08 CN disclosed
CN-110291118-A Acrylic rubber 日本瑞翁株式会社 2019-09-27 CN disclosed
CN-110183780-A Polypropylene wiredrawing material, its PP Pipe Compound and BOPP film product 国家能源投资集团有限责任公司 2019-08-30 CN disclosed
CN-110172136-A A kind of composition epoxy resin of resisting high-temperature yellowing and preparation method thereof 深圳市安品有机硅材料有限公司 2019-08-27 CN disclosed
CN-107709503-B Gas sealant member composition and gas sealant member 日本瑞翁株式会社 2019-06-18 CN disclosed
CN-107075182-B Rubber cross object 日本瑞翁株式会社 2019-03-19 CN disclosed
CN-109196040-A Polyolefin compositions 道达尔研究技术弗吕公司 2019-01-11 CN disclosed
CN-109196599-A Moisture-curable composition comprising silane-grafted polyolefin elastomer and halogen-free flame retardant 陶氏环球技术有限责任公司 2019-01-11 CN disclosed
CN-108641175-A A kind of wearable lightweight Cable jacket materials and preparation method thereof 安徽电信器材贸易工业有限责任公司 2018-10-12 CN disclosed
CN-105778493-B Amilan polyamide resin composition and formed body 旭化成株式会社 2018-10-12 CN disclosed
CN-107709503-A Gas sealant member composition and gas sealant member 日本瑞翁株式会社 2018-02-16 CN disclosed
CN-104220227-B Sulfide and preparation method thereof 电化株式会社 2017-12-15 CN disclosed
CN-107075182-A Rubber cross thing 日本瑞翁株式会社 2017-08-18 CN disclosed
CN-104662078-B Rubber composition, its sulfide and products formed 电化株式会社 2016-10-19 CN disclosed