Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4361482 | 0.78 | KDM5A (0.33) | KDM4EALDH1A1KDM5AADORA2AADORA1 | |
| SCHEMBL8233937 | 0.77 | ADORA2A (0.37) | KDM4EALDH1A1KDM5AADORA2AADORA1 | |
| SCHEMBL24848624 | 0.77 | PIK3CD (0.31) | KDM5AADORA2AADORA1 | |
| SCHEMBL27878769 | 0.77 | KDM5A (0.30) | KDM5AADORA2AADORA1 | |
| SCHEMBL26161133 | 0.74 | ADORA2A (0.32) | KDM5AADORA2AADORA1 | |
| SCHEMBL16654819 | 0.74 | — | — | |
| SCHEMBL15723770 | 0.73 | KDM5A (0.34) | KDM5AADORA2AADORA1 | |
| SCHEMBL15723768 | 0.73 | LRRK2 (0.36) | ALDH1A1SMN1; SMN2KDM5AAR | |
| SCHEMBL28932516 | 0.69 | ADORA2A (0.40) | ADORA2AADORA1 | |
| SCHEMBL15808415 | 0.67 | HTT (0.36) | KDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530436-A | A kind of pyrazole compound and its preparation method and application | 黄传满 | 2018-09-14 | — | — | CN | disclosed |