Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | DNMT1 | P26358 | 5/20 | 0.64 |
| ▸ | DNMT3A | Q9Y6K1 | 4/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.64 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369587 | 0.87 | HTR2C (0.67) | RAB9ADNMT1DNMT3ADNMT3LMAPT | |
| SCHEMBL15923019 | 0.87 | DNMT1 (0.57) | RAB9ADNMT1DNMT3AHDAC3ACHE | |
| SCHEMBL21346884 | 0.84 | GAA (0.61) | KDM4EMAPTALDH1A1HPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL21332758 | 0.83 | GAA (0.60) | KDM4EMAPTALDH1A1HPGDCYP1A2 | |
| SCHEMBL29822716 | 0.80 | DNMT1 (0.75) | RAB9ADNMT1DNMT3AHDAC3ACHE | |
| SCHEMBL1891738 | 0.80 | DNMT1 (0.75) | RAB9ADNMT1DNMT3AHDAC3ACHE | |
| SCHEMBL28238219 | 0.80 | DNMT1 (0.78) | DNMT1DNMT3AHDAC3ACHEHDAC1 | |
| SCHEMBL12217987 | 0.80 | DNMT1 (0.78) | DNMT1DNMT3AHDAC3ACHEHDAC1 | |
| Hydrochloric Acid SCHEMBL1887938 | 0.79 | DNMT1 (0.73) | RAB9ADNMT1DNMT3AHDAC3ACHE | |
| SCHEMBL31696329 | 0.79 | DNMT1 (0.73) | DNMT1DNMT3AHDAC3ACHEHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358841-B | 4- ((2-substituted quinoline-4-yl) amino) benzoyl hydrazine derivatives, and preparation method and application thereof | 厦门大学 | 2020-11-10 | — | — | CN | disclosed |
| CN-108358841-A | A kind of 4- ((2- substd quinolines -4- bases) amino) benzoyl hydrazine analog derivative and the preparation method and application thereof | 厦门大学 | 2018-08-03 | — | — | CN | disclosed |