Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 6/20 | 0.75 |
| ▸ | DNMT3A | Q9Y6K1 | 5/20 | 0.75 |
| ▸ | DNMT3L | Q9UJW3 | 2/20 | 0.75 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.75 |
| ▸ | ACHE | P22303 | 1/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.75 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.75 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.75 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.75 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.75 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.63 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1891738 | 1.00 | DNMT1 (0.75) | DNMT1DNMT3ADNMT3LHDAC3ACHE | |
| Hydrochloric Acid SCHEMBL1887938 | 0.99 | DNMT1 (0.73) | DNMT1DNMT3ADNMT3LHDAC3ACHE | |
| SCHEMBL5357863 | 0.90 | DNMT1 (0.61) | DNMT1DNMT3ADNMT3LHDAC3ACHE | |
| SCHEMBL12218327 | 0.87 | DNMT1 (0.73) | DNMT1DNMT3ADNMT3LHDAC3ACHE | |
| SCHEMBL31696329 | 0.87 | DNMT1 (0.73) | DNMT1DNMT3ADNMT3LHDAC3ACHE | |
| SCHEMBL13140149 | 0.86 | DNMT1 (0.95) | DNMT1DNMT3ADNMT3LHDAC3ACHE | |
| SCHEMBL12217951 | 0.86 | DNMT1 (0.95) | DNMT1DNMT3ADNMT3LHDAC3ACHE | |
| Hydrochloric Acid SCHEMBL27756932 | 0.86 | DNMT1 (0.71) | DNMT1DNMT3ADNMT3LHDAC3ACHE | |
| SCHEMBL12217987 | 0.85 | DNMT1 (0.78) | DNMT1DNMT3ADNMT3LHDAC3ACHE | |
| SCHEMBL28238219 | 0.85 | DNMT1 (0.78) | DNMT1DNMT3ADNMT3LHDAC3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853670-B | Quinoline compound containing amide group and preparation and application thereof | 沈阳药科大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-114853670-A | Amide group-containing quinoline compound and preparation and application thereof | 沈阳药科大学 | 2022-08-05 | — | — | CN | disclosed |