Acrylic Acid

Acrylic Acid

SCHEMBL28239256

C=CC(=O)O.O=C(Cl)Oc1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
KDM4E B2RXH2 4/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TGM2 P21980 2/20 0.42
AKT1 P31749 1/20 0.42
TDP1 Q9NUW8 3/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALOX15 P16050 3/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
LMNA P02545 1/20 0.40
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
EGFR P00533 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27488948 0.90 THRB (0.50) THRBKDM4EMEN1KMT2ASMN1; SMN2
SCHEMBL3302 0.87 TDP1 (0.50) KDM4ETDP1ATML3MBTL1ALOX15
SCHEMBL370622 0.87 TDP1 (0.50) KDM4ETDP1ATML3MBTL1ALOX15
Benzene SCHEMBL7925278 0.87 TDP1 (0.50) KDM4ETDP1ATML3MBTL1ALOX15
SCHEMBL11224568 0.85 TDP1 (0.48) KDM4ETDP1ATML3MBTL1ALOX15
Hydrochloric Acid SCHEMBL3896561 0.85 TDP1 (0.48) KDM4ETDP1ATML3MBTL1ALOX15
SCHEMBL10975650 0.85 TDP1 (0.48) KDM4ETDP1ATML3MBTL1ALOX15
SCHEMBL27326182 0.85 TDP1 (0.48) KDM4ETDP1ATML3MBTL1ALOX15
Bicarbonate SCHEMBL29032037 0.85 TDP1 (0.48) KDM4ETDP1ATML3MBTL1ALOX15
SCHEMBL27902340 0.85 TDP1 (0.48) KDM4ETDP1ATML3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108503998-A A kind of shock resistance PVC material and preparation method thereof using waste PET material preparation 赵旭 2018-09-07 CN disclosed