Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of 1-Hydroxy-2-Ethoxybenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL28519 | 0.90 | GAA (0.64) | GAAMAPTJAK2LMNAL3MBTL1 | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL28239475 | 0.90 | GAA (0.64) | GAAMAPTJAK2LMNAL3MBTL1 | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL29579232 | 0.90 | GAA (0.64) | GAAMAPTJAK2LMNAL3MBTL1 | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL28203721 | 0.88 | GAA (0.57) | GAAMAPTJAK2LMNAL3MBTL1 | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL30617187 | 0.88 | GAA (0.61) | GAAMAPTJAK2LMNAL3MBTL1 | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL28372945 | 0.88 | GAA (0.61) | GAAMAPTJAK2LMNAL3MBTL1 | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL31092904 | 0.88 | GAA (0.61) | GAAMAPTJAK2LMNAL3MBTL1 | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL8054034 | 0.88 | GAA (0.61) | GAAMAPTJAK2LMNAL3MBTL1 | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL31092902 | 0.88 | GAA (0.61) | GAAMAPTJAK2LMNAL3MBTL1 | |
| 1-Hydroxy-2-Ethoxybenzene SCHEMBL27476572 | 0.88 | GAA (0.61) | GAAMAPTJAK2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658291-A | A method of it reducing o-ethoxyphenol and produces Determination of Volatile Phenol in Refinery Wastewater content | 重庆欣欣向荣精细化工有限公司 | 2018-10-16 | — | — | CN | disclosed |