SCHEMBL28239403

SCHEMBL28239403

CCCCCCCCCCCCCCCCCC1=C(CCCCCCCC)C1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCD O00767 1/20 0.68
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.47
ALDH1A1 P00352 3/20 0.40
PTGS2 P35354 3/20 0.39
ESR1 P03372 2/20 0.39
ADRA2A P08913 2/20 0.39
ADORA3 P0DMS8 2/20 0.39
TACR2 P21452 2/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
KCNH2 Q12809 2/20 0.39
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
SHBG P04278 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
HSPD1 P10809 1/20 0.39
ADRB3 P13945 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753696 1.00 SCD (0.68) SCDTSHRTHRBALDH1A1PTGS2
SCHEMBL11238492 1.00 SCD (0.68) SCDTSHRTHRBALDH1A1PTGS2
SCHEMBL3802053 0.97 SCD (0.64) SCDTSHRTHRBALDH1A1PTGS2
SCHEMBL320624 0.88 SCD (0.54) SCDTSHRTHRBALDH1A1LMNA
SCHEMBL5352187 0.87 SCD (0.55) SCDTSHRTHRBALDH1A1KDM4E
SCHEMBL10594490 0.87 SCD (0.55) SCDTSHRTHRBALDH1A1KDM4E
SCHEMBL7935931 0.87 SCD (0.55) SCDTSHRTHRBALDH1A1KDM4E
SCHEMBL5342472 0.87 SCD (0.55) SCDTSHRTHRBALDH1A1KDM4E
SCHEMBL8951764 0.87 SCD (0.55) SCDTSHRTHRBALDH1A1KDM4E
SCHEMBL8951776 0.87 SCD (0.55) SCDTSHRTHRBALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105916839-B cationic lipid 卫材R&D管理有限公司 2018-09-18 CN disclosed