Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3802053 | 0.90 | SCD (0.64) | SCDTSHRLMNATHRBALDH1A1 | |
| SCHEMBL7753696 | 0.88 | SCD (0.68) | SCDTSHRLMNATHRBALDH1A1 | |
| SCHEMBL11238492 | 0.88 | SCD (0.68) | SCDTSHRLMNATHRBALDH1A1 | |
| SCHEMBL6283167 | 0.85 | SCD (0.43) | SCDTSHRLMNATHRBALDH1A1 | |
| SCHEMBL5365766 | 0.85 | SCD (0.43) | SCDTSHRLMNATHRBALDH1A1 | |
| SCHEMBL7749957 | 0.83 | SCD (0.52) | SCDTSHRTHRBALDH1A1 | |
| SCHEMBL10447160 | 0.81 | — | — | |
| SCHEMBL10985090 | 0.79 | SCD (0.53) | SCDTSHRLMNATHRBALDH1A1 | |
| SCHEMBL7754788 | 0.78 | SCD (0.92) | SCDTSHRLMNAALDH1A1NPSR1 | |
| SCHEMBL7754017 | 0.78 | TSHR (0.58) | SCDTSHRLMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173691-B1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | UNIV NORTH CAROLINA STATE (US) | 2013-11-13 | — | — | EP | disclosed |
| US-20130137575-A1 | CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-05-30 | — | — | US | disclosed |
| US-8329954-B2 | Cyclopropene amine compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-12-11 | — | — | US | disclosed |
| US-20120035269-A1 | CYCLOPROPENE AMINE COMPOUNDS | SISLER EDWARD C (US) | 2012-02-09 | — | — | US | disclosed |
| US-8093430-B2 | Methods of inhibiting ethylene responses in plants using cyclopropene amine compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-10 | — | — | US | disclosed |
| EP-2173691-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | North Carolina State University (US) | 2010-04-14 | — | — | EP | disclosed |
| US-20090124504-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY | 2009-05-14 | — | — | US | disclosed |
| WO-2009002407-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035269-A1 | CYCLOPROPENE AMINE COMPOUNDS | PNMT, EDNRB, CNR1 | SCD 2174/4885TSHR 1062/4885LMNA 4451/4885 |
| US-20130137575-A1 | CYCLOPROPENE AMINE COMPOUNDS | PNMT, EDNRB, CNR1 | SCD 2174/4885TSHR 1062/4885LMNA 4451/4885 |
| US-20090124504-A1 | METHODS OF INHIBITING ETHYLENE RESPONSES IN PLANTS USING CYCLOPROPENE AMINE COMPOUNDS | EDNRB, EDNRA, ECE1 | SCD 1687/4885TSHR 1206/4885LMNA 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.