Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15451912 | 0.93 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACA2CHKA | |
| SCHEMBL17809482 | 0.93 | ALDH1A1 (0.54) | ALDH1A1EPHX2SPRMEN1KMT2A | |
| SCHEMBL13450558 | 0.91 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ACA2CHKA | |
| SCHEMBL4815774 | 0.84 | ALDH1A1 (0.52) | ALDH1A1SPRMEN1KMT2ACA2 | |
| SCHEMBL17177148 | 0.84 | ALDH1A1 (0.50) | ALDH1A1SPRMEN1KMT2ACA2 | |
| SCHEMBL4815766 | 0.84 | ALDH1A1 (0.52) | ALDH1A1SPRMEN1KMT2ACA2 | |
| SCHEMBL18855601 | 0.82 | ALDH1A1 (0.56) | ALDH1A1SPRMEN1KMT2ACA2 | |
| SCHEMBL15759336 | 0.81 | FFAR3 (0.38) | ALDH1A1EPHX2SPRMEN1KMT2A | |
| SCHEMBL11997948 | 0.81 | EPHX2 (0.53) | ALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL18390501 | 0.80 | CYP1A2 (0.45) | ALDH1A1SPRMAPTHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370909-B | Tricyclic compound | ABBVIE 公司 | 2018-09-11 | — | — | CN | disclosed |