Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11995110 | 0.83 | HDAC1 (0.37) | HDAC1HDAC6TP53MAPTNOTUM | |
| SCHEMBL9842129 | 0.80 | HDAC1 (0.35) | HDAC1HDAC6TP53MAPTNOTUM | |
| SCHEMBL3795637 | 0.80 | KDM1A (0.40) | HDAC1HDAC6TP53MAPTNOTUM | |
| SCHEMBL9842388 | 0.80 | HDAC1 (0.40) | HDAC1HDAC6TP53MAPTNOTUM | |
| SCHEMBL9842393 | 0.80 | NOTUM (0.39) | HDAC1HDAC6TP53MAPTNOTUM | |
| SCHEMBL9842125 | 0.80 | MAPT (0.35) | HDAC1HDAC6TP53MAPTNOTUM | |
| SCHEMBL2782656 | 0.79 | GSK3B (0.37) | HDAC1HDAC6TP53MAPTNOTUM | |
| SCHEMBL11408486 | 0.79 | KDM1A (0.35) | HDAC1HDAC6TP53MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL3937688 | 0.78 | KDM1A (0.39) | HDAC1HDAC6TP53MAPTNOTUM | |
| Iodide SCHEMBL3292671 | 0.78 | KDM1A (0.39) | HDAC1HDAC6TP53MAPTNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108516973-A | 3- benzothiazoles -1- (3- dimethylaminos) propyl quinoline -4- ketone derivatives and its preparation method and application | 广西师范大学 | 2018-09-11 | — | — | CN | disclosed |
| CN-104122341-B | The detection method of benazolin acetic acid in a kind of plant-derived food | INSTITUTE OF AGRICULTURAL QUALITY STANDARDS AND TESTING TECHNOLOGY, HENAN ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2015-10-28 | — | — | CN | disclosed |