SCHEMBL11408486

SCHEMBL11408486

[CH2]CCCCCN1CSc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 9/20 0.35
PIM1 P11309 1/20 0.35
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
SIGMAR1 Q99720 2/20 0.32
MAOA P21397 1/20 0.32
TP53 P04637 2/20 0.32
MAPT P10636 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
SLC22A1 O15245 1/20 0.30
PRNP P04156 1/20 0.30
CYP1A2 P05177 1/20 0.30
ADRB2 P07550 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
HTR1A P08908 1/20 0.30
CHRM5 P08912 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9064444 0.84 LMNA (0.43) KDM1AKDM4EMEN1ALDH1A1KMT2A
SCHEMBL9037704 0.84 LMNA (0.43) KDM1AKDM4EMEN1ALDH1A1KMT2A
SCHEMBL9722988 0.84 LMNA (0.43) KDM1AKDM4EMEN1ALDH1A1KMT2A
SCHEMBL29306541 0.84 LMNA (0.43) KDM1AKDM4EMEN1ALDH1A1KMT2A
Bromide SCHEMBL9625797 0.83 ALDH1A1 (0.45) KDM1AKDM4EMEN1ALDH1A1KMT2A
Iodide SCHEMBL9038446 0.83 LMNA (0.42) KDM1AKDM4EMEN1ALDH1A1KMT2A
Bromide SCHEMBL9694372 0.83 ALDH1A1 (0.45) KDM1AKDM4EMEN1ALDH1A1KMT2A
Perchlorate SCHEMBL10913596 0.83 KDM1A (0.35) KDM1APIM1KDM4EMEN1ALDH1A1
SCHEMBL4304928 0.82 KDM1A (0.43) KDM1AKDM4EMEN1ALDH1A1KMT2A
SCHEMBL9715453 0.80 KDM1A (0.48) KDM1AKDM4EALDH1A1MAOATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4237214-A P-DIHYDROXYBENZENE DEVELOPING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1980-12-02 US disclosed