Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL27316347 | 0.91 | ALDH1A1 (0.62) | ALDH1A1HSD17B10EPHX2EPHX1LMNA | |
| Octanedioate SCHEMBL27980166 | 0.89 | EPHX1 (0.62) | ALDH1A1HSD17B10EPHX2EPHX1LMNA | |
| Sebacic Acid SCHEMBL27980336 | 0.89 | EPHX1 (0.62) | ALDH1A1HSD17B10EPHX2EPHX1LMNA | |
| SCHEMBL27746143 | 0.89 | ALDH1A1 (0.55) | ALDH1A1HSD17B10EPHX2EPHX1SMN1; SMN2 | |
| SCHEMBL27980159 | 0.89 | EPHX1 (0.62) | ALDH1A1HSD17B10EPHX2EPHX1LMNA | |
| Malonic Acid SCHEMBL11176995 | 0.88 | ALDH1A1 (0.60) | ALDH1A1HSD17B10EPHX2EPHX1LMNA | |
| Beta-Alanine SCHEMBL27834027 | 0.87 | ALDH1A1 (0.53) | ALDH1A1HSD17B10EPHX2EPHX1SMN1; SMN2 | |
| Butyric Acid SCHEMBL27421296 | 0.87 | ALDH1A1 (0.53) | ALDH1A1HSD17B10EPHX2EPHX1SMN1; SMN2 | |
| Propionic Acid SCHEMBL9069175 | 0.86 | ALDH1A1 (0.57) | ALDH1A1HSD17B10EPHX2EPHX1LMNA | |
| Glycolic Acid SCHEMBL28077117 | 0.86 | ALDH1A1 (0.57) | ALDH1A1HSD17B10EPHX2EPHX1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112029564-B | Neutral water-based antirust agent | 南京科润工业介质股份有限公司 | 2022-06-28 | — | — | CN | claimed |
| CN-112029564-B | Neutral water-based antirust agent | 南京科润工业介质股份有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-112028764-B | Preparation method and application of dodecenylsuccinic acid amine salt | 南京科润工业介质股份有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-112028764-A | Preparation method and application of dodecenylsuccinic acid amine salt | 南京科润工业介质股份有限公司 | 2020-12-04 | — | — | CN | disclosed |
| CN-112029564-A | Neutral water-based antirust agent | 南京科润工业介质股份有限公司 | 2020-12-04 | — | — | CN | disclosed |
| CN-108500511-A | The manufacturing method of flux composition, solder composition, electric substrate and electric substrate | 株式会社田村制作所 | 2018-09-07 | — | — | CN | disclosed |