SCHEMBL28240352

SCHEMBL28240352

CNC(=O)c1ccccc1.Cc1ccc(C(=O)Oc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 1/20 0.59
KMT2A Q03164 5/20 0.57
MEN1 O00255 3/20 0.57
MAPT P10636 5/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
POLB P06746 2/20 0.51
PARP10 Q53GL7 1/20 0.51
LMNA P02545 1/20 0.51
CCR6 P51684 1/20 0.49
ALDH1A1 P00352 1/20 0.49
PKM P14618 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
HPGD P15428 1/20 0.49
TSHR P16473 1/20 0.49
HTT P42858 1/20 0.49
MAPK14 Q16539 1/20 0.48
PRSS1 P07477 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL104409 0.87 PARP10 (0.59) KMT2AMEN1MAPTTDP1L3MBTL1
SCHEMBL11584711 0.85 PARP10 (0.62) KMT2AMEN1MAPTTDP1L3MBTL1
SCHEMBL26038899 0.85 PARP10 (0.68) KMT2AMEN1MAPTTDP1L3MBTL1
SCHEMBL15382236 0.85 PARP10 (0.68) KMT2AMEN1MAPTTDP1L3MBTL1
SCHEMBL28239332 0.85 MAPT (0.51) MMP13KMT2AMEN1MAPTPOLB
Benzoic Acid 4-Methylphenyl Ester SCHEMBL1546372 0.84 KMT2A (0.66) KMT2AMEN1MAPTTDP1L3MBTL1
SCHEMBL13415306 0.82 SMN1; SMN2 (0.56) KMT2AMAPTTDP1L3MBTL1PARP10
SCHEMBL8638980 0.81 PARP10 (0.57) MMP13KMT2AMEN1MAPTTDP1
SCHEMBL26038990 0.81 SMN1; SMN2 (0.58) KMT2AMEN1MAPTTDP1L3MBTL1
SCHEMBL26038968 0.81 PARP10 (0.62) KMT2AMEN1MAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108517022-A For the ingredient of solid catalyst and its catalyst of olefinic polymerization and application 北京利和知信科技有限公司 2018-09-11 CN disclosed
CN-108517021-A A kind of ingredient of solid catalyst, catalyst and its application being suitable for producing broad molecular weight distribution polymers 北京利和知信科技有限公司 2018-09-11 CN disclosed