SCHEMBL28239332

SCHEMBL28239332

CNC(=O)c1ccccc1.Cc1ccc(C(=O)Oc2ccccc2)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.51
KDM4E B2RXH2 3/20 0.51
MAPK1 P28482 1/20 0.51
MMP13 P45452 1/20 0.49
POLB P06746 1/20 0.47
HPGD P15428 2/20 0.45
ALDH1A1 P00352 2/20 0.45
GAA P10253 2/20 0.45
GLA P06280 1/20 0.45
ATM Q13315 1/20 0.45
KMT2A Q03164 6/20 0.45
MEN1 O00255 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.43
PTK2B Q14289 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
ALOX12 P18054 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8422589 0.87 MAPT (0.53) MAPTKDM4EMAPK1POLBHPGD
SCHEMBL28240352 0.85 MMP13 (0.59) MAPTMMP13POLBHPGDALDH1A1
SCHEMBL28901019 0.80 KCNMA1 (0.59) MAPTKDM4EMAPK1HPGDALDH1A1
SCHEMBL4351853 0.78 MAPT (0.54) MAPTKDM4EMAPK1POLBHPGD
SCHEMBL29011919 0.77 KMT2A (0.55) MAPTPOLBALDH1A1GAAKMT2A
SCHEMBL4358292 0.75 HPGD (0.51) MAPTKDM4EMAPK1POLBHPGD
SCHEMBL4363059 0.75 HPGD (0.58) MAPTKDM4EMAPK1POLBHPGD
SCHEMBL28343567 0.75 MAPT (0.58) MAPTKDM4EMAPK1POLBHPGD
SCHEMBL29444237 0.74 MAPT (0.67) MAPTKDM4EMAPK1HPGDALDH1A1
SCHEMBL12430329 0.74 MAPT (0.52) MAPTKDM4EMAPK1POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108517022-A For the ingredient of solid catalyst and its catalyst of olefinic polymerization and application 北京利和知信科技有限公司 2018-09-11 CN disclosed
CN-108517021-A A kind of ingredient of solid catalyst, catalyst and its application being suitable for producing broad molecular weight distribution polymers 北京利和知信科技有限公司 2018-09-11 CN disclosed