Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27227 | 0.84 | THRB (0.33) | SIGMAR1MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9618005 | 0.84 | THRB (0.33) | SIGMAR1MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL3222970 | 0.78 | CHRM5 (0.43) | SIGMAR1NOS1NOS2CYP1A2MEN1 | |
| SCHEMBL1524658 | 0.78 | CHRM5 (0.43) | SIGMAR1NOS1NOS2CYP1A2MEN1 | |
| SCHEMBL6533680 | 0.78 | CHRM5 (0.43) | SIGMAR1NOS1NOS2CYP1A2MEN1 | |
| SCHEMBL23070439 | 0.78 | CHRM5 (0.43) | SIGMAR1NOS1NOS2CYP1A2MEN1 | |
| SCHEMBL187659 | 0.78 | CHRM5 (0.43) | SIGMAR1NOS1NOS2CYP1A2MEN1 | |
| SCHEMBL6532715 | 0.78 | CHRM5 (0.43) | SIGMAR1NOS1NOS2CYP1A2MEN1 | |
| SCHEMBL1930290 | 0.78 | CHRM5 (0.43) | SIGMAR1NOS1NOS2CYP1A2MEN1 | |
| SCHEMBL11006113 | 0.78 | CHRM5 (0.43) | SIGMAR1NOS1NOS2CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503555-A | 4- ((4- (dimethylamino) cyclohexyl) methyl) cyclohexanol and preparation method and application | 万华化学集团股份有限公司 | 2018-09-07 | — | — | CN | disclosed |