Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30552348 | 0.82 | GSK3B (0.49) | GSK3BDYRK1AATRCYP17A1PSMB8 | |
| SCHEMBL26235624 | 0.82 | GSK3B (0.49) | GSK3BDYRK1AATRCYP17A1PSMB8 | |
| SCHEMBL1950652 | 0.76 | BRD9 (0.42) | ATRMETAP1LMNA | |
| SCHEMBL6815230 | 0.75 | NAMPT (0.49) | ATRCYP17A1PSMB8NAMPTMAP4K4 | |
| SCHEMBL8425212 | 0.74 | — | — | |
| SCHEMBL25836666 | 0.74 | L3MBTL1 (0.49) | ATRL3MBTL1CA1CA2NAMPT | |
| SCHEMBL31645606 | 0.74 | ATR (0.35) | ATRL3MBTL1CA1CA2KDM4E | |
| SCHEMBL28949328 | 0.73 | L3MBTL1 (0.35) | ATRL3MBTL1CA1CA2KDM4E | |
| SCHEMBL30125665 | 0.72 | GSK3B (0.45) | GSK3BDYRK1AATRCYP17A1CA1 | |
| SCHEMBL31600979 | 0.72 | GSK3B (0.48) | GSK3BDYRK1ASCN9AMAP4K4SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108570048-A | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2018-09-25 | — | — | CN | disclosed |