SCHEMBL28242578

SCHEMBL28242578

NC(=O)c1ccc2ccccc2c1C(=O)NC1CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.54
RAB9A P51151 9/20 0.54
KDM4E B2RXH2 2/20 0.54
ALDH1A1 P00352 2/20 0.54
HPGD P15428 2/20 0.54
HTT P42858 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
NR1I2 O75469 1/20 0.54
AHR P35869 1/20 0.54
MAPT P10636 2/20 0.51
EPHX1 P07099 1/20 0.50
TP53 P04637 1/20 0.50
POLB P06746 2/20 0.49
TAS1R3 Q7RTX0 1/20 0.49
TAS1R1 Q7RTX1 1/20 0.49
TAS1R2 Q8TE23 1/20 0.49
LMNA P02545 1/20 0.49
GAA P10253 2/20 0.48
KMT2A Q03164 2/20 0.48
RXFP1 Q9HBX9 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67733 0.91 NPC1 (0.58) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL29481000 0.91 NPC1 (0.58) NPC1RAB9AKDM4EALDH1A1HPGD
Biphenyl SCHEMBL21812299 0.81 KMT2A (0.42) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL19358683 0.78 NPC1 (0.52) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL3456146 0.77 NPC1 (0.65) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL3954720 0.77 NPC1 (0.65) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL30073645 0.77 NPC1 (0.65) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL18041117 0.77 ALDH1A1 (0.69) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL30804522 0.77 HDAC8 (0.54) KDM4EALDH1A1SMN1; SMN2POLBGAA
SCHEMBL3031297 0.77 HDAC8 (0.54) KDM4EALDH1A1SMN1; SMN2POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105612241-B light stabilizer composition and resin composition thereof 株式会社艾迪科 2018-09-25 CN disclosed