Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25763595 | 0.88 | CA12 (0.47) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL11702223 | 0.85 | SMN1; SMN2 (0.36) | PTGS2GUSBTSHRHTTLMNA | |
| SCHEMBL23362891 | 0.83 | PTGS2 (0.43) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL30888540 | 0.83 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11196313 | 0.83 | CA12 (0.47) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL31335892 | 0.81 | KMT2A (0.43) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL22833407 | 0.81 | TSHR (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31158895 | 0.81 | CA12 (0.41) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL6742562 | 0.81 | GUSB (0.45) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL13280402 | 0.79 | PTGS2 (0.40) | PTGS2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415362-A | Imidazo [1,2-a] pyridine derivate, Its Preparation Method And Use | 第药品株式会社 | 2019-03-01 | — | — | CN | disclosed |
| CN-108602805-A | Isoindoline, azaisoindoline, indenone and the dihydro azepine indone inhibitor of MNK1 and MNK2 | 效应治疗股份有限公司 | 2018-09-28 | — | — | CN | disclosed |