Phosphine

Phosphine

SCHEMBL28243264

CCCCCNC(Cc1ccc(O)cc1)C(=O)O.P

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.50
ACE P12821 3/20 0.49
MME P08473 3/20 0.49
CPA1 P15085 2/20 0.49
ACE2 Q9BYF1 2/20 0.49
GRIA1 P42261 2/20 0.47
NAALAD2 Q9Y3Q0 1/20 0.47
CHRND Q07001 5/20 0.46
CHRNA1 P02708 1/20 0.46
CHRNG P07510 1/20 0.46
CHRNB1 P11230 1/20 0.46
PLG P00747 1/20 0.46
PLAU P00749 1/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
SIGMAR1 Q99720 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4850535 0.99 FOLH1 (0.51) FOLH1ACEMMECPA1ACE2
SCHEMBL4850530 0.99 FOLH1 (0.51) FOLH1ACEMMECPA1ACE2
SCHEMBL23778217 0.97 GRIA1 (0.50) FOLH1ACEMMECPA1ACE2
SCHEMBL38651117 0.97 GRIA1 (0.50) FOLH1ACEMMECPA1ACE2
SCHEMBL28031750 0.97 GRIA1 (0.50) FOLH1ACEMMECPA1ACE2
SCHEMBL28379862 0.97 GRIA1 (0.50) FOLH1ACEMMECPA1ACE2
SCHEMBL28663068 0.97 GRIA1 (0.50) FOLH1ACEMMECPA1ACE2
Ammonia Solution, Strong SCHEMBL28124004 0.97 FOLH1 (0.50) FOLH1ACEMMECPA1ACE2
SCHEMBL8975007 0.97 GRIA1 (0.50) FOLH1ACEMMECPA1ACE2
SCHEMBL620471 0.97 GRIA1 (0.50) FOLH1ACEMMECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108588035-A Virus or the Novel stabilisation method of bacterium 白血球保健股份有限公司 2018-09-28 CN disclosed