SCHEMBL620471

SCHEMBL620471

CCCCCCCCCCCCCCCCCCN[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 5/20 0.50
FOLH1 Q04609 1/20 0.50
CHRND Q07001 5/20 0.49
CHRNA1 P02708 1/20 0.49
CHRNG P07510 1/20 0.49
CHRNB1 P11230 1/20 0.49
MME P08473 1/20 0.49
ACE P12821 1/20 0.49
CPA1 P15085 1/20 0.49
ACE2 Q9BYF1 1/20 0.49
PLG P00747 1/20 0.48
PLAU P00749 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
NAALAD2 Q9Y3Q0 1/20 0.47
CNR1 P21554 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28031750 1.00 GRIA1 (0.50) GRIA1FOLH1CHRNDCHRNA1CHRNG
SCHEMBL620470 1.00 GRIA1 (0.50) GRIA1FOLH1CHRNDCHRNA1CHRNG
SCHEMBL7142929 1.00 GRIA1 (0.50) GRIA1FOLH1CHRNDCHRNA1CHRNG
SCHEMBL28663068 1.00 GRIA1 (0.50) GRIA1FOLH1CHRNDCHRNA1CHRNG
SCHEMBL8975007 1.00 GRIA1 (0.50) GRIA1FOLH1CHRNDCHRNA1CHRNG
SCHEMBL23778217 1.00 GRIA1 (0.50) GRIA1FOLH1CHRNDCHRNA1CHRNG
SCHEMBL28379862 1.00 GRIA1 (0.50) GRIA1FOLH1CHRNDCHRNA1CHRNG
SCHEMBL38651117 1.00 GRIA1 (0.50) GRIA1FOLH1CHRNDCHRNA1CHRNG
Hydrochloric Acid SCHEMBL906368 0.99 GRIA1 (0.49) GRIA1FOLH1CHRNDCHRNA1CHRNG
Hydrochloric Acid SCHEMBL906366 0.99 GRIA1 (0.49) GRIA1FOLH1CHRNDCHRNA1CHRNG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1585 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12582711-B2 RNA-based adjuvant to enhance the immune response to vaccines and therapeutics ImmuneSure LLC (US) 2026-03-24 US claimed
EP-4487869-A2 RNA ENCODING A TUMOR ANTIGEN CureVac SE (DE) 2025-01-08 EP claimed
EP-2068918-B2 VACCINE COMPOSITION CONTAINING SYNTHETIC ADJUVANT ACCESS TO ADVANCED HEALTH INST (US) 2024-07-03 EP claimed
EP-4324832-A2 IMMUNOMODULATORY COMPOUNDS AND USE THEREOF FOR THE TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES AC BioScience SA (CH) 2024-02-21 EP claimed
US-20230355749-A1 Immunomodulatory Compounds And Use Thereof For The Treatment And/Or Prevention Of Infectious Diseases AC BIOSCIENCE SA (CH) 2023-11-09 US claimed
EP-4216997-A1 IMMUNOMODULATORY COMPOUNDS AND USE THEREOF FOR THE TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES AC BioScience SA (CH) 2023-08-02 EP claimed
US-20230165954-A1 RNA-BASED ADJUVANT TO ENHANCE THE IMMUNE RESPONSE TO VACCINES AND THERAPEUTICS ImmuneSure LLC 2023-06-01 US claimed
US-11376325-B2 Method of inducing an immune response using an expression construct and GLA ACCESS TO ADVANCED HEALTH INSTITUTE (US) 2022-07-05 US claimed
WO-2022063858-A1 IMMUNOMODULATORY COMPOUNDS AND USE THEREOF FOR THE TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES AC BIOSCIENCE SA (CH) 2022-03-31 WO claimed
EP-3973986-A1 IMMUNOMODULATORY COMPOUNDS AND USE THEREOF FOR THE TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES AC BioScience SA (CH) 2022-03-30 EP claimed
EP-0597838-A1 VACCINE COMPOSITIONS NORTH AMERICAN VACCINE, INC. (CA) 1994-05-25 EP claimed
WO-1994005325-A1 VACCINES AGAINST GROUP C NEISSERIA MENINGITIDIS NORTH AMERICAN VACCINE, INC. (US) 1994-03-17 WO claimed
EP-0549617-A1 IMPROVED VACCINE COMPOSITIONS. NORTH AMERICAN VACCINE INC (CA) 1993-07-07 EP claimed
WO-1992004915-A1 IMPROVED VACCINE COMPOSITIONS NORTH AMERICAN VACCINE, INC. (CA) 1992-04-02 WO claimed
WO-1991016926-A1 VACCINE COMPOSITIONS NORTH AMERICAN VACCINE, INC. (CA) 1991-11-14 WO claimed
EP-0018189-B1 SYNTHETIC ADJUVANTS FOR STIMULATING ANTIGENIC RESPONSES CONNAUGHT LABORATORIES LIMITED (CA) 1984-09-12 EP claimed
US-4428932-A ALLERGY DESENSITIZATION BEECHAM GROUP LIMITED (GB) 1984-01-31 US claimed
EP-0064366-A1 Pharmaceutical compositions BEECHAM GROUP PLC (GB) 1982-11-10 EP claimed
US-4258029-A LONG CHAIN ALCOHOL ESTERS OF AMINO ACIDS CONNAUGHT LABORATORIES LIMITED (CA) 1981-03-24 US claimed
EP-0018189-A2 Synthetic adjuvants for stimulating antigenic responses CONNAUGHT LABORATORIES LIMITED (CA) 1980-10-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11376325-B2 Method of inducing an immune response using an expression construct and GLA TLR7, TLR3, TLR6 GRIA1 654/4885FOLH1 2525/4885CHRND 3669/4885
US-20230355749-A1 Immunomodulatory Compounds And Use Thereof For The Treatment And/Or Prevention Of Infectious Diseases CD14, TLR9, TLR3 GRIA1 3490/4885FOLH1 3671/4885CHRND 3037/4885
US-12582711-B2 RNA-based adjuvant to enhance the immune response to vaccines and therapeutics METTL16, RBM28, RBM26 GRIA1 4551/4885FOLH1 1973/4885CHRND 712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.