SCHEMBL28243284

SCHEMBL28243284

C=C(C)C(C)n1ccnc1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 6/20 0.40
CYP17A1 P05093 7/20 0.39
CYP26A1 O43174 1/20 0.37
KDM4E B2RXH2 1/20 0.36
TBXA2R P21731 1/20 0.35
NFKB1 P19838 1/20 0.34
QPCT Q16769 1/20 0.34
HSD17B10 Q99714 1/20 0.34
QPCTL Q9NXS2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17484629 0.79 KDM4E (0.42) CYP19A1CYP17A1CYP26A1KDM4ETBXA2R
SCHEMBL28177904 0.79 KDM4E (0.42) CYP19A1CYP17A1CYP26A1KDM4ETBXA2R
SCHEMBL20518637 0.75 KDM4E (0.45) CYP19A1CYP17A1CYP26A1KDM4ETBXA2R
SCHEMBL2585276 0.75 KDM4E (0.45) CYP19A1CYP17A1CYP26A1KDM4ETBXA2R
SCHEMBL2990565 0.75
Bromide SCHEMBL28354965 0.73 KDM4E (0.44) CYP19A1CYP17A1CYP26A1KDM4ETBXA2R
SCHEMBL27673215 0.73 KDM4E (0.41) CYP19A1CYP17A1CYP26A1KDM4ETBXA2R
Hydrochloric Acid SCHEMBL27966647 0.73 KDM4E (0.44) CYP19A1CYP17A1CYP26A1KDM4ETBXA2R
SCHEMBL4171040 0.73 KDM4E (0.41) CYP19A1CYP17A1CYP26A1KDM4ETBXA2R
SCHEMBL76770 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107001976-A The method for improving the anti-coking of lubricating composition NYCO公司 2017-08-01 CN claimed
CN-108530363-A Glyoxaline ion liquid, il electrolyte and preparation method and application 河北工业大学 2018-09-14 CN disclosed