Tert-Butanol

Tert-Butanol

SCHEMBL28244705

CC(C)(C)Br.CC(C)(C)O

nearest known ligand 0.36

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
THRB P10828 1/20 0.36
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9680302 0.82
SCHEMBL2300235 0.82
SCHEMBL948623 0.82
Tert-Butanol SCHEMBL282 0.82
Tert-Butanol SCHEMBL3628777 0.82
Tert-Butanol SCHEMBL20503401 0.82 ALDH1A1 (0.46) ALDH1A1THRBTSHR
Tert-Butanol SCHEMBL788666 0.82 ALDH1A1 (0.46) ALDH1A1THRBTSHR
SCHEMBL6775241 0.82
SCHEMBL22538 0.82
Tert-Butanol SCHEMBL6152871 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108658908-B 1,3- bis- replaces ketene compounds and its application 广州必贝特医药技术有限公司 2019-05-10 CN disclosed
CN-108658908-A 1,3- bis- substitution ketene compounds and its application 广州必贝特医药技术有限公司 2018-10-16 CN disclosed