Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | PDXK | O00764 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.42 |
| ▸ | PNPO | Q9NVS9 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29004448 | 0.92 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL27524467 | 0.92 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL28177479 | 0.90 | TRIM24 (0.47) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL27581870 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL28517132 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL28558160 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL27437788 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL28049059 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL1545975 | 0.78 | PDXK (0.53) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL29086551 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108472339-A | Methods for cancer treatment in mammals, including humans, using methionine and asparagine depletion | 爱瑞泰克药物公司 | 2018-08-31 | — | — | CN | disclosed |