Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761733 | 0.88 | MAOB (0.61) | MAOBSIRT1MAOARAB9AKMT2A | |
| SCHEMBL31314554 | 0.80 | MAOB (0.50) | MAOBSIRT1MAOARAB9AKMT2A | |
| SCHEMBL333141 | 0.78 | CYP3A4 (0.55) | KMT2ASMN1; SMN2MAPTTP53HPGD | |
| SCHEMBL29387256 | 0.78 | CYP3A4 (0.55) | KMT2ASMN1; SMN2MAPTTP53HPGD | |
| SCHEMBL6345667 | 0.77 | KMT2A (0.61) | MAOBSIRT1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11734978 | 0.77 | MAOB (0.48) | MAOBSIRT1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL1299217 | 0.77 | MAOB (0.58) | MAOBMAOARAB9AADORA2BNPC1 | |
| SCHEMBL10669335 | 0.75 | CYP3A4 (0.59) | KMT2ASMN1; SMN2MAPTTP53HPGD | |
| SCHEMBL70456 | 0.74 | MAOB (0.76) | MAOBMAOARAB9AADORA2BNPC1 | |
| SCHEMBL12325233 | 0.74 | MAOB (0.63) | MAOBSIRT1MAOARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484546-B | A kind of preparation method of 2- methyl -3- benzoyl benzofuran derivatives | 江南大学 | 2019-11-08 | — | — | CN | claimed |
| CN-108484546-A | A kind of preparation method of 2- methyl -3- benzoyl benzofuran derivatives | 江南大学 | 2018-09-04 | — | — | CN | claimed |
| CN-108484546-B | A kind of preparation method of 2- methyl -3- benzoyl benzofuran derivatives | 江南大学 | 2019-11-08 | — | — | CN | disclosed |
| CN-108484546-B | A kind of preparation method of 2- methyl -3- benzoyl benzofuran derivatives | 江南大学 | 2019-11-08 | — | — | CN | disclosed |
| CN-108484546-B | A kind of preparation method of 2- methyl -3- benzoyl benzofuran derivatives | 江南大学 | 2019-11-08 | — | — | CN | disclosed |
| CN-108484546-A | A kind of preparation method of 2- methyl -3- benzoyl benzofuran derivatives | 江南大学 | 2018-09-04 | — | — | CN | disclosed |
| CN-108484546-A | A kind of preparation method of 2- methyl -3- benzoyl benzofuran derivatives | 江南大学 | 2018-09-04 | — | — | CN | disclosed |