Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.73 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TDO2 | P48775 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL9110913 | 0.94 | POLB (0.84) | POLBNCOA1NCOA3CYP1A2TSHR | |
| SCHEMBL538895 | 0.90 | POLB (0.77) | POLBNCOA1NCOA3CYP1A2TSHR | |
| SCHEMBL30531716 | 0.89 | POLB (0.74) | POLBNCOA1NCOA3CYP1A2TSHR | |
| SCHEMBL29611471 | 0.85 | POLB (1.00) | POLBNCOA1NCOA3CYP1A2TSHR | |
| SCHEMBL827685 | 0.85 | POLB (1.00) | POLBNCOA1NCOA3CYP1A2TSHR | |
| SCHEMBL29750649 | 0.85 | POLB (1.00) | POLBNCOA1NCOA3CYP1A2TSHR | |
| Quinoline SCHEMBL27814435 | 0.85 | POLB (0.64) | POLBNCOA1NCOA3CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL7950313 | 0.83 | POLB (0.96) | POLBNCOA1NCOA3CYP1A2TSHR | |
| Quinoline SCHEMBL28344417 | 0.80 | ALDH1A1 (0.52) | POLBNCOA1NCOA3CYP1A2TSHR | |
| Quinoline SCHEMBL28125435 | 0.80 | POLB (0.61) | POLBNCOA1NCOA3CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108610286-A | A kind of 2- aryl-4-quinolones derivative and its preparation method and application | 绍兴文理学院 | 2018-10-02 | — | — | CN | disclosed |