Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 4/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28245274 | 1.00 | POLB (0.46) | POLBL3MBTL1ACERENLMNA | |
| SCHEMBL15233566 | 0.86 | POLB (0.47) | POLBL3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL1122394 | 0.85 | POLB (0.46) | POLBL3MBTL1ACERENLMNA | |
| SCHEMBL1777982 | 0.84 | POLB (0.48) | POLBL3MBTL1ACERENFFAR1 | |
| SCHEMBL4066863 | 0.84 | POLB (0.48) | POLBL3MBTL1ACERENFFAR1 | |
| SCHEMBL1777983 | 0.84 | POLB (0.48) | POLBL3MBTL1ACERENFFAR1 | |
| SCHEMBL12719567 | 0.81 | CHRM2 (0.45) | POLBL3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL7522820 | 0.80 | POLB (0.42) | POLBL3MBTL1PEPDFFAR1RAB9A | |
| SCHEMBL4444071 | 0.80 | DPP4 (0.42) | POLBL3MBTL1ACERENLMNA | |
| SCHEMBL5643023 | 0.80 | POLB (0.42) | POLBL3MBTL1FFAR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104918615-B | The method for treating hepatopathy | 扎夫根股份有限公司 | 2018-10-12 | — | — | CN | disclosed |