Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.60 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28245361 | 1.00 | PTGS1 (0.64) | PTGS1PTGS2MAOBMAOACXCL12 | |
| SCHEMBL28245358 | 0.84 | MAOB (0.74) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL28245356 | 0.84 | MAOB (0.74) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL28404511 | 0.82 | FGFR1 (0.59) | PTGS1PTGS2MAOBMAOACXCL12 | |
| SCHEMBL28404514 | 0.82 | FGFR1 (0.59) | PTGS1PTGS2MAOBMAOACXCL12 | |
| SCHEMBL22667858 | 0.82 | MAPT (0.63) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL28458356 | 0.82 | MAPT (0.63) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL28458698 | 0.82 | MAOB (0.69) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL28458699 | 0.82 | MAOB (0.69) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL30214859 | 0.81 | MAOB (0.64) | MAOBMAOAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558807-A | The method of one pot process cumarin base chalcone compounds | 河南中烟工业有限责任公司 | 2018-09-21 | — | — | CN | disclosed |