Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.69 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | AR | P10275 | 4/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.55 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.55 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28458699 | 1.00 | MAOB (0.69) | MAOBMAOAMEN1KMT2AAR | |
| SCHEMBL4397459 | 0.88 | AR (0.65) | MAOBMAOAMEN1KMT2AAR | |
| SCHEMBL4397462 | 0.88 | AR (0.65) | MAOBMAOAMEN1KMT2AAR | |
| SCHEMBL13857231 | 0.87 | MAOB (0.67) | MAOBMAOAMEN1KMT2AKDM4E | |
| SCHEMBL28470319 | 0.86 | MEN1 (0.65) | MAOBMAOAMEN1KMT2AKDM4E | |
| SCHEMBL28245359 | 0.83 | MAOB (0.75) | MAOBMEN1KMT2AARCYP1A1 | |
| SCHEMBL28245355 | 0.83 | MAOB (0.75) | MAOBMEN1KMT2AARCYP1A1 | |
| SCHEMBL28245362 | 0.82 | PTGS1 (0.64) | MAOBMAOAMEN1KMT2AAR | |
| SCHEMBL28245361 | 0.82 | PTGS1 (0.64) | MAOBMAOAMEN1KMT2AAR | |
| SCHEMBL28459080 | 0.81 | MAOB (0.73) | MAOBMAOAMEN1KMT2ACYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111588718-B | Alpha-glucosidase inhibitor and application thereof | 五邑大学 | 2021-06-08 | — | — | CN | disclosed |
| CN-111588718-A | Alpha-glucosidase inhibitor and application thereof | 五邑大学 | 2020-08-28 | — | — | CN | disclosed |