Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL8597277 | 0.97 | ALDH1A1 (0.61) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| Methacrylic Acid SCHEMBL1173108 | 0.97 | ALDH1A1 (0.61) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| Methacrylic Acid SCHEMBL6231225 | 0.97 | ALDH1A1 (0.61) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| Methacrylic Acid SCHEMBL11071941 | 0.95 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| Methacrylic Acid SCHEMBL15485306 | 0.95 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| Methacrylic Acid SCHEMBL6009531 | 0.95 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| Methacrylic Acid SCHEMBL11041664 | 0.95 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| Methacrylic Acid SCHEMBL1890911 | 0.92 | ALDH1A1 (0.55) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| Methacrylic Acid SCHEMBL28174783 | 0.92 | ALDH1A1 (0.55) | ALDH1A1TSHRFGFR4TDP1LMNA | |
| Methacrylic Acid SCHEMBL28878259 | 0.92 | TDP1 (0.60) | ALDH1A1TSHRFGFR4TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108604676-A | The manufacturing method of electrode for secondary battery active material, solid electrolyte composition, solid state secondary battery electrode slice and solid state secondary battery and electrode for secondary battery active material, solid state secondary battery electrode slice and solid state secondary battery | 富士胶片株式会社 | 2018-09-28 | — | — | CN | disclosed |