Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.63 |
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | ILK | Q13418 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | SNCA | P37840 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL27636836 | 0.92 | KDM4E (0.69) | KDM4EMAPTRAB9ANPC1NPSR1 | |
| SCHEMBL196475 | 0.92 | KDM4E (0.73) | KDM4EMAPTRAB9ANPC1NPSR1 | |
| SCHEMBL30132720 | 0.92 | KDM4E (0.73) | KDM4EMAPTRAB9ANPC1NPSR1 | |
| SCHEMBL1549628 | 0.90 | KDM4E (0.71) | KDM4EMAPTRAB9ANPC1NPSR1 | |
| SCHEMBL359505 | 0.90 | KDM4E (0.71) | KDM4EMAPTRAB9ANPC1NPSR1 | |
| SCHEMBL1550056 | 0.90 | KDM4E (0.71) | KDM4EMAPTRAB9ANPC1NPSR1 | |
| SCHEMBL1549967 | 0.90 | KDM4E (0.76) | KDM4EMAPTRAB9ANPC1NPSR1 | |
| SCHEMBL11910018 | 0.90 | KDM4E (0.71) | KDM4EMAPTRAB9ANPC1NPSR1 | |
| SCHEMBL3261894 | 0.90 | KDM4E (0.71) | KDM4EMAPTRAB9ANPC1NPSR1 | |
| SCHEMBL1549970 | 0.90 | KDM4E (0.71) | KDM4EMAPTRAB9ANPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108641712-A | The preparation method of the warm white macromolecule complex fluorescent powder of the zinc of terbium containing europium | 太原理工大学 | 2018-10-12 | — | — | CN | claimed |