Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18759619 | 0.89 | TDP1 (0.61) | TDP1LMNAMAPK1HIF1AKMT2A | |
| SCHEMBL14402754 | 0.89 | TDP1 (0.61) | TDP1LMNAMAPK1HIF1AKMT2A | |
| SCHEMBL28803760 | 0.84 | TDP1 (0.56) | TDP1LMNAMAPK1HIF1AKMT2A | |
| SCHEMBL8470979 | 0.82 | LMNA (0.63) | TDP1LMNAMAPK1HIF1AKMT2A | |
| SCHEMBL2776358 | 0.82 | TDP1 (0.53) | TDP1LMNAMAPK1HIF1AKMT2A | |
| SCHEMBL27463287 | 0.81 | LMNA (0.61) | TDP1LMNAMAPK1HIF1AKMT2A | |
| Hydrochloric Acid SCHEMBL27944480 | 0.81 | TDP1 (0.51) | TDP1LMNAMAPK1HIF1AKMT2A | |
| SCHEMBL3678120 | 0.78 | HDAC3 (0.57) | TDP1KMT2AMEN1RAB9A | |
| SCHEMBL8727360 | 0.78 | TDP1 (0.49) | TDP1LMNAMAPK1HIF1AKMT2A | |
| SCHEMBL21820641 | 0.78 | TDP1 (0.71) | TDP1LMNAMAPK1HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104693193-B | Aryl methoxy isoindoline derivative and composition and their application method including it | 细胞基因公司 | 2018-09-18 | — | — | CN | disclosed |