SCHEMBL28246780

SCHEMBL28246780

CCCC(O)C(C=O)C=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
TSHR P16473 4/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CHRM1 P11229 1/20 0.35
AKR1A1 P14550 1/20 0.35
CHRM3 P20309 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GAPDH P04406 2/20 0.34
TRPA1 O75762 1/20 0.34
DDAH1 O94760 1/20 0.34
MAPT P10636 1/20 0.34
CYP3A4 P08684 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17984947 0.79
SCHEMBL1782596 0.77
SCHEMBL5499873 0.77
SCHEMBL28247921 0.76
SCHEMBL18211561 0.75
SCHEMBL16600571 0.75 LMNA (0.38) LMNATSHRSMN1; SMN2CHRM1AKR1A1
SCHEMBL20530446 0.75 LMNA (0.43) LMNATSHRSMN1; SMN2CHRM1AKR1A1
SCHEMBL730338 0.75 LMNA (0.43) LMNATSHRSMN1; SMN2CHRM1AKR1A1
SCHEMBL28159286 0.73 LMNA (0.46) LMNATSHRSMN1; SMN2CHRM1AKR1A1
Water SCHEMBL6553209 0.73 LMNA (0.41) LMNATSHRSMN1; SMN2CHRM1AKR1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108585948-B Method for modifying surface of alumina-based ceramic fiber 山东大学 2021-04-23 CN disclosed
CN-108585948-A A kind of method that aluminium oxide base ceramic fibre surface is modified 山东大学 2018-09-28 CN disclosed