Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | FABP2 | P12104 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2833063 | 0.81 | HSD11B1 (0.41) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL2829910 | 0.77 | PPARG (0.32) | PPARACYP2C19PPARGCYP2C9PPARD | |
| SCHEMBL2827329 | 0.70 | PPARA (0.39) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL2827328 | 0.69 | HSD11B1 (0.47) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL2827326 | 0.69 | HSD11B1 (0.47) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL2823665 | 0.67 | HSD11B1 (0.39) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL2830535 | 0.65 | PPARA (0.48) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL2824066 | 0.65 | HSD11B1 (0.42) | HSD11B1HSD11B2 | |
| SCHEMBL2829490 | 0.65 | HSD11B1 (0.39) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL2829492 | 0.65 | HSD11B1 (0.39) | PPARACYP1A2CYP3A4CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243479-A2 | Novel amide and amidine derivates and uses thereof | Abbott Laboratories (US) | 2010-10-27 | — | — | EP | disclosed |