Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.37 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL27878577 | 1.00 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL13368687 | 0.97 | CES2 (0.58) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL9013430 | 0.97 | CES2 (0.58) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL8294928 | 0.97 | CES2 (0.58) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL2154567 | 0.97 | CES2 (0.58) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL1420 | 0.97 | — | — | |
| SCHEMBL16317826 | 0.97 | CES2 (0.58) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL9010935 | 0.97 | CES2 (0.58) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL1477908 | 0.97 | CES2 (0.58) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL21391824 | 0.94 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083927-B | Phosphino- amidine compound, metal complex, antigravity system and their oligomeric or olefin polymerization purposes | 切弗朗菲利浦化学公司 | 2018-10-26 | — | — | CN | disclosed |