O-Xylene

O-Xylene

SCHEMBL28248447

CCCC#N.Cc1ccccc1C

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
ACHE P22303 2/20 0.48
HTT P42858 3/20 0.41
KDM4E B2RXH2 1/20 0.38
DRD3 P35462 1/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 5/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 2/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11430215 0.86 AR (0.38) TSHRACHEHTTKDM4EDRD3
Toluene SCHEMBL3036821 0.84 TSHR (0.50) TSHRACHEHTTKDM4EDRD3
O-Xylene SCHEMBL28119922 0.83 TSHR (0.50) TSHRACHEHTTKDM4EKMT2A
O-Xylene SCHEMBL27880864 0.82 TSHR (0.56) TSHRACHEHTTKDM4EKMT2A
Biphenyl SCHEMBL27497370 0.81 ALDH1A1 (0.43) TSHRKDM4EDRD3KMT2AMEN1
P-Xylene SCHEMBL28290544 0.80 ALDH1A1 (0.46) TSHRACHEHTTDRD3KMT2A
Biphenyl SCHEMBL27962812 0.79 ALDH1A1 (0.41) TSHRKDM4EDRD3ALDH1A1SMN1; SMN2
Benzene SCHEMBL27516340 0.79 TSHR (0.53) TSHRHTTDRD3KMT2AMEN1
O-Xylene SCHEMBL28180385 0.77 TSHR (0.56) TSHRACHEHTTKDM4EKMT2A
O-Xylene SCHEMBL28897630 0.76 TSHR (0.71) TSHRACHEHTTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715601-A Diaza dialkenyl compound, film form the manufacturing method with raw material and film 株式会社ADEKA 2019-05-03 CN disclosed
CN-105214653-B A kind of preparation method of carbon nanotube loaded nanoparticle catalyst 北京化工大学 2018-09-21 CN disclosed