Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 12/20 | 0.50 |
| ▸ | DRD3 | P35462 | 11/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501263 | 0.80 | NOTUM (0.56) | NOTUMDRD2DRD3ALOX5 | |
| SCHEMBL6496702 | 0.80 | NOTUM (0.56) | NOTUMDRD2DRD3ALOX5 | |
| SCHEMBL3537217 | 0.76 | DRD2 (0.74) | NOTUMDRD2DRD3ALOX5 | |
| SCHEMBL29809089 | 0.76 | DRD2 (0.74) | NOTUMDRD2DRD3ALOX5 | |
| SCHEMBL4468086 | 0.75 | DRD2 (0.72) | NOTUMDRD2DRD3ALOX5 | |
| SCHEMBL6498980 | 0.74 | NOTUM (0.48) | NOTUMDRD2DRD3CYP2D6 | |
| SCHEMBL6497130 | 0.74 | NOTUM (0.48) | NOTUMDRD2DRD3CYP2D6 | |
| SCHEMBL21624919 | 0.73 | NOTUM (0.63) | NOTUMDRD2DRD3ALOX5 | |
| SCHEMBL21624920 | 0.73 | NOTUM (0.63) | NOTUMDRD2DRD3ALOX5 | |
| SCHEMBL3602267 | 0.73 | NOTUM (0.67) | NOTUMDRD2DRD3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727249-A | The synthetic method of 3- difluoromethyls piperidine hydrochlorate and its derivative | 台州学院 | 2018-11-02 | — | — | CN | disclosed |