Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14854426 | 0.87 | MDM2 (0.39) | KMT2AMEN1MAPTSMN1; SMN2KDM4A | |
| SCHEMBL3418485 | 0.87 | PTGDR2 (0.44) | KMT2AMEN1MAPTSMN1; SMN2KDM4A | |
| Bromide SCHEMBL5458775 | 0.86 | PTGS1 (0.39) | KMT2AMEN1MAPTSMN1; SMN2KDM4A | |
| Bromide SCHEMBL14843908 | 0.86 | MDM2 (0.39) | KMT2AMEN1MAPTSMN1; SMN2KDM4A | |
| SCHEMBL23724052 | 0.84 | APEX1 (0.36) | KMT2AMEN1MAPTSMN1; SMN2KDM4A | |
| SCHEMBL28395116 | 0.84 | SMN1; SMN2 (0.36) | KMT2AMEN1MAPTSMN1; SMN2KDM4A | |
| SCHEMBL1065475 | 0.84 | APEX1 (0.36) | KMT2AMEN1MAPTSMN1; SMN2KDM4A | |
| SCHEMBL25230632 | 0.84 | GAA (0.41) | MAPTGAAPTGS1PTGS2PTGER4 | |
| Bromide SCHEMBL861823 | 0.83 | APEX1 (0.35) | KMT2AMEN1MAPTSMN1; SMN2KDM4A | |
| SCHEMBL1067864 | 0.83 | APEX1 (0.35) | KMT2AMEN1MAPTSMN1; SMN2KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752319-A | Monoamine oxidase A inhibitor indoles cyanines coupling compound and its preparation method and application | 沈阳药科大学 | 2018-11-06 | — | — | CN | disclosed |