SCHEMBL1065475

SCHEMBL1065475

CC1N(CCCCCC(=O)O)c2ccc(S(=O)(=O)O)cc2C1(C)C

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 2/20 0.36
MEN1 O00255 1/20 0.36
KDM4A O75164 1/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 2/20 0.34
ALDH1A1 P00352 3/20 0.34
TBXA2R P21731 1/20 0.34
GNRHR P30968 1/20 0.34
CYP26B1 Q9NR63 1/20 0.33
PKM P14618 1/20 0.33
RORC P51449 1/20 0.33
HTT P42858 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23724052 1.00 APEX1 (0.36) APEX1SMN1; SMN2POLBMEN1KDM4A
Bromide SCHEMBL861823 0.99 APEX1 (0.35) APEX1SMN1; SMN2POLBMEN1KDM4A
SCHEMBL1067864 0.99 APEX1 (0.35) APEX1SMN1; SMN2POLBMEN1KDM4A
SCHEMBL28395116 0.91 SMN1; SMN2 (0.36) SMN1; SMN2POLBMEN1KDM4AMAPT
SCHEMBL881399 0.88 APEX1 (0.34) APEX1SMN1; SMN2POLBGAAALDH1A1
SCHEMBL1069437 0.85 SMN1; SMN2 (0.38) APEX1SMN1; SMN2POLBMEN1KDM4A
SCHEMBL6018477 0.85 MEN1 (0.35) SMN1; SMN2POLBMEN1KDM4AMAPT
SCHEMBL15137506 0.84 POLB (0.32) APEX1SMN1; SMN2POLBGAARORC
SCHEMBL28249171 0.84 KMT2A (0.38) SMN1; SMN2POLBMEN1KDM4AMAPT
SCHEMBL2677869 0.84 MEN1 (0.36) SMN1; SMN2POLBMEN1KDM4AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807904-B2 FRET-labeled compounds and uses therefor PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-11-07 US disclosed
US-11186870-B2 FRET-labeled compounds and uses therefor PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2021-11-30 US disclosed
US-20200318178-A1 FRET-LABELED COMPOUNDS AND USES THEREFOR PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2020-10-08 US disclosed
US-10570445-B2 Fret-labeled compounds and uses therefor PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2020-02-25 US disclosed
US-20190032117-A1 FRET-LABELED COMPOUNDS AND USES THEREFOR PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2019-01-31 US disclosed
US-10066258-B2 FRET-labeled compounds and uses therefor PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2018-09-04 US disclosed
US-20170159111-A1 FRET-LABELED COMPOUNDS AND USES THEREFOR PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2017-06-08 US disclosed
EP-2912464-B1 HYDROXAMATE SUBSTITUTED AZAINDOLINE-CYANINE DYES AND BIOCONJUGATES OF THE SAME BECTON DICKINSON CO (US) 2017-04-26 EP disclosed
EP-2758475-B1 DYES FOR LABELLING MOLECULAR LIGANDS ILLUMINA CAMBRIDGE LTD (GB) 2017-04-26 EP disclosed
US-9551660-B2 Method for detecting reactants using fluorescent signal intensity PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2017-01-24 US disclosed
EP-1849837-A2 Luminescent compounds Terpetschnig, Ewald A. (US) 2007-10-31 EP disclosed
US-7250517-B2 Luminescent compounds Terpetschnig, Ewald A. (US) 2007-07-31 US disclosed
US-20040166515-A1 Luminescent compounds TERPETSCHNIG, EWALD A. 2004-08-26 US disclosed
EP-1394219-A1 PH sensitive cyanine dyes as reactive fluorescent reagents CARNEGIE-MELLON UNIVERSITY (US) 2004-03-03 EP disclosed
US-20030235846-A1 Luminescent compounds TERPTETSCHNIG, EWALD A. 2003-12-25 US disclosed
US-6579718-B1 For detecting and quantifying peptides, polypeptides and proteins; sensitive, facile and does not require use of organic solvents MOLECULAR PROBES, INC. 2003-06-17 US disclosed
EP-1078023-A4 LUMINESCENT COMPOUNDS TERPETSCHNIG EWALD A (US) 2003-03-26 EP disclosed
US-6538129-B1 Luminescent compounds Terpetschnig, Ewald A. 2003-03-25 US disclosed
EP-1078023-A1 LUMINESCENT COMPOUNDS Terpetschnig, Ewald A. (US) 2001-02-28 EP disclosed
WO-1999051702-A1 LUMINESCENT COMPOUNDS TERPETSCHNIG EWALD A (US) 1999-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11186870-B2 FRET-labeled compounds and uses therefor METTL16, TARBP1, RNGTT APEX1 418/4885SMN1; SMN2 3724/4885POLB 125/4885
US-10570445-B2 Fret-labeled compounds and uses therefor METTL16, TARBP1, RNGTT APEX1 418/4885SMN1; SMN2 3724/4885POLB 125/4885
US-20030235846-A1 Luminescent compounds CROCC, NR2E1, NDC1 APEX1 2373/4885SMN1; SMN2 3356/4885POLB 3904/4885
US-20190032117-A1 FRET-LABELED COMPOUNDS AND USES THEREFOR METTL16, TARBP1, RNGTT APEX1 418/4885SMN1; SMN2 3724/4885POLB 125/4885
US-20040166515-A1 Luminescent compounds RORC, NR2E3, RORB APEX1 1869/4885SMN1; SMN2 2378/4885POLB 4011/4885
US-20200318178-A1 FRET-LABELED COMPOUNDS AND USES THEREFOR METTL16, TARBP1, RNGTT APEX1 418/4885SMN1; SMN2 3724/4885POLB 125/4885
US-11807904-B2 FRET-labeled compounds and uses therefor METTL16, BCDIN3D, GARS1 APEX1 483/4885SMN1; SMN2 3059/4885POLB 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.