SCHEMBL2824928

SCHEMBL2824928

CCS(=O)(=O)C(C)[O]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3110204 0.78
SCHEMBL27982336 0.76
SCHEMBL10181306 0.74 CA2 (0.37)
SCHEMBL148219 0.74
SCHEMBL3105085 0.74 CA2 (0.48)
SCHEMBL1981760 0.69 CA1 (0.35)
SCHEMBL8091228 0.69
SCHEMBL5199514 0.69
SCHEMBL6707408 0.69
SCHEMBL6531820 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1731505-B1 ALKOXYPHENYLPROPANOIC ACID DERIVATIVES TAKEDA PHARMACEUTICAL (JP) 2015-01-14 EP disclosed
US-8222417-B2 Compound having 11β-HSD1 inhibitory activity TAISHO PHARMACEUTICAL CO., LTD (JP) 2012-07-17 US disclosed
EP-2253315-A1 Alkoxyphenylpropanoic acid derivatives Takeda Pharmaceutical Company Limited (JP) 2010-11-24 EP disclosed
US-20100179325-A1 COMPOUND HAVING 11BETA-HSD1 INHIBITORY ACTIVITY TAISHO PHARMACEUTICAL CO., LTD. (JP) 2010-07-15 US disclosed
EP-2172453-A1 COMPOUND HAVING 11 ß-HSD1 INHIBITORY ACTIVITY Taisho Pharmaceutical Co. Ltd. (JP) 2010-04-07 EP disclosed
US-7517910-B2 Alkoxyphenylpropanoic acid derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-04-14 US disclosed
EP-1614003-B1 PHOTOGRAPHIC COLOUR MATERIAL CONTAINING A RESORCINOL DERIVATIVE AS BLACK COUPLER FUJIFILM CORP (JP) 2008-02-27 EP disclosed
US-7323294-B2 Photographic colour material containing a resorcinol derivative as black coupler FUJI PHOTO FILM CO., LTD. (JP) 2008-01-29 US disclosed
US-20070213364-A1 Alkoxyphenylpropanoic Acid Derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-09-13 US disclosed
US-7250249-B2 Black and white photothermographic material FUJIFILM CORPORATION (JP) 2007-07-31 US disclosed
EP-1311500-A2 INDOLE, AZAINDOLE AND INDAZOLE DERIVATIVES HAVING VEGF INHIBITING ACTIVITY AstraZeneca AB (SE) 2003-05-21 EP disclosed
WO-2002012227-A2 INDOLE, AZAINDOLE AND INDAZOLE DERIVATIVES HAVING VEGF INHIBITING ACTIVITY ASTRAZENECA AB (SE) 2002-02-14 WO disclosed
US-6124341-A A DRUG FOR TREATING HYPERTENSION, CONGESTIVE HEART FAILURE, RESTENOSIS FOLLOWING ARTERIAL INJURY, CEREBRAL OR MYOCARDIAL ISCHEMIA OR ATHEROSCLEROSIS; VASODILUTOR ABBOTT LABORATORIES (US) 2000-09-26 US disclosed
EP-0991620-A1 PYRROLIDINE CARBOXYLIC ACID DERIVATIVES AS ENDOTHELIN ANTAGONISTS Abbott Laboratories (US) 2000-04-12 EP disclosed
WO-1998057933-A1 PYRROLIDINE CARBOXYLIC ACID DERIVATIVES AS ENDOTHELIN ANTAGONISTS ABBOTT LABORATORIES (US) 1998-12-23 WO disclosed
US-4495270-A RAPIDLY FORMS IMAGES HAVING HIGH IMAGE DENSITY FUJI PHOTO FILM CO., LTD. (JP) 1985-01-22 US disclosed
US-4430423-A CYAN DYE FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1984-02-07 US disclosed
US-4429035-A NONSILVER PHOTOGRAPHY, OXIDATIVE COUPLING FUJI PHOTO FILM CO., LTD. (JP) 1984-01-31 US disclosed
US-4327173-A CYANINE DYE-FORMING COUPLER; HEAT RESISTANCE; PHOTOSTABILITY; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1982-04-27 US disclosed
US-4302466-A NEMATOCIDES, ARTHROPODICIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-11-24 US disclosed