SCHEMBL28249690

SCHEMBL28249690

O[C@H]1CCCC1(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.39
OPRL1 P41146 1/20 0.39
HTR1A P08908 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28248386 1.00 AKR1C1 (0.39) AKR1C1OPRL1HTR1A
SCHEMBL23198926 1.00 AKR1C1 (0.39) AKR1C1OPRL1HTR1A
SCHEMBL13853046 0.89 OPRL1 (0.43) OPRL1
SCHEMBL22436648 0.87 HTR1A (0.44) HTR1A
SCHEMBL170243 0.82 SLC18A3 (0.45) HTR1A
SCHEMBL1866342 0.78 CNR2 (0.40) AKR1C1OPRL1
SCHEMBL1955880 0.75 SLC18A3 (0.47) AKR1C1HTR1A
SCHEMBL12276561 0.75 SLC18A3 (0.47) AKR1C1HTR1A
SCHEMBL1958981 0.75 SLC18A3 (0.47) AKR1C1HTR1A
SCHEMBL1954906 0.75 SLC18A3 (0.47) AKR1C1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108741062-A A kind of coptis active material 浦江县美泽生物科技有限公司 2018-11-06 CN claimed
CN-108720008-A The method that active material is extracted from rapeseed 金华市胤宏农业科技有限公司 2018-11-02 CN claimed
CN-108741062-A A kind of coptis active material 浦江县美泽生物科技有限公司 2018-11-06 CN disclosed