Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.58 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3272975 | 0.88 | S1PR5 (0.49) | GBA1S1PR5S1PR1FUCA1RORC | |
| SCHEMBL19532468 | 0.87 | S1PR5 (0.48) | GBA1S1PR5S1PR1FUCA1RORC | |
| SCHEMBL3273128 | 0.83 | S1PR5 (0.45) | GBA1S1PR5S1PR1FUCA1RORC | |
| SCHEMBL14759416 | 0.82 | GBA1 (0.75) | GBA1S1PR5S1PR1FUCA1RORC | |
| SCHEMBL14759418 | 0.82 | GBA1 (0.75) | GBA1S1PR5S1PR1FUCA1RORC | |
| SCHEMBL1190716 | 0.82 | GBA1 (0.75) | GBA1S1PR5S1PR1FUCA1RORC | |
| SCHEMBL742926 | 0.82 | GBA1 (0.75) | GBA1S1PR5S1PR1FUCA1RORC | |
| SCHEMBL9685026 | 0.82 | FUCA1 (0.63) | GBA1S1PR5S1PR1FUCA1RORC | |
| SCHEMBL3369886 | 0.79 | GBA1 (0.51) | GBA1S1PR5S1PR1TSHR | |
| SCHEMBL13105233 | 0.79 | GBA1 (0.51) | GBA1S1PR5S1PR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779123-A | Fused tetracyclic compound, its composition and purposes | 泰博生物科技有限公司 | 2018-11-09 | — | — | CN | disclosed |