Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.63 |
| ▸ | GBA1 | P04062 | 1/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4522412 | 0.87 | FUCA1 (0.67) | FUCA1GBA1S1PR5S1PR1RORC | |
| SCHEMBL21806309 | 0.87 | FUCA1 (0.54) | FUCA1S1PR5ALDH1A1NPC1RAB9A | |
| SCHEMBL3544810 | 0.87 | ALDH1A1 (0.52) | FUCA1S1PR5ALDH1A1NPC1RAB9A | |
| SCHEMBL3544805 | 0.87 | ALDH1A1 (0.52) | FUCA1S1PR5ALDH1A1NPC1RAB9A | |
| SCHEMBL3544813 | 0.87 | ALDH1A1 (0.52) | FUCA1S1PR5ALDH1A1NPC1RAB9A | |
| SCHEMBL18652827 | 0.84 | FUCA1 (0.63) | FUCA1GBA1S1PR5S1PR1RORC | |
| SCHEMBL27556877 | 0.84 | ALDH1A1 (0.61) | FUCA1ALDH1A1GAA | |
| SCHEMBL500851 | 0.84 | S1PR5 (0.48) | FUCA1S1PR5S1PR1RORCSIRT1 | |
| SCHEMBL500852 | 0.84 | S1PR5 (0.48) | FUCA1S1PR5S1PR1RORCSIRT1 | |
| SCHEMBL500850 | 0.84 | S1PR5 (0.48) | FUCA1S1PR5S1PR1RORCSIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288519-A4 | 1-TERTIARY-ALKYL-SUBSTITUTED NAPHTHYRIDINE- AND QUINOLINE-CARBOXYLIC ACID ANTIBACTERIAL AGENTS | — | 1992-04-15 | — | — | EP | disclosed |
| US-4965273-A | Certain 1-tertiary-butyl-naphthyridone carboxylic acid derivatives anti-bacterial agents | BRISTOL-MYERS COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4954507-A | 1-tertiary-alkyl-substituted naphthyridine carboxylic acid antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0288519-A1 | 1-TERTIARY-ALKYL-SUBSTITUTED NAPHTHYRIDINE- AND QUINOLINE-CARBOXYLIC ACID ANTIBACTERIAL AGENTS | Bristol-Myers Squibb Company (US) | 1988-11-02 | — | — | EP | disclosed |
| EP-0266576-A2 | 1-Tert-alkyl-substituted naphthyridine and quinoline carboxylic acids as antibacterial agents | Bristol-Myers Squibb Company (US) | 1988-05-11 | — | — | EP | disclosed |
| WO-1988002627-A1 | 1-TERTIARY-ALKYL-SUBSTITUTED NAPHTHYRIDINE- AND QUINOLINE-CARBOXYLIC ACID ANTIBACTERIAL AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-04-21 | — | — | WO | disclosed |