Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28091052 | 0.85 | KDM4E (0.48) | TBXA2RTBXAS1LMNAKMT2AHSD17B10 | |
| SCHEMBL27916776 | 0.82 | MEN1 (0.40) | LMNAKMT2AHSD17B10 | |
| Naphthalene SCHEMBL27735937 | 0.77 | MEN1 (0.37) | KMT2A | |
| SCHEMBL29240842 | 0.77 | KDM4E (0.48) | KDM4ENAPRTHCAR2SMN1; SMN2TSHR | |
| SCHEMBL27859643 | 0.72 | KDM4E (0.46) | KDM4ENAPRTHCAR2SMN1; SMN2TSHR | |
| SCHEMBL28061261 | 0.71 | KMT2A (0.33) | LMNAKMT2ANAPRTTSHRALDH1A1 | |
| SCHEMBL27970673 | 0.71 | KMT2A (0.33) | LMNAKMT2ANAPRTTSHRALDH1A1 | |
| SCHEMBL28016232 | 0.70 | MEN1 (0.32) | LMNAKMT2ANAPRTTSHRALDH1A1 | |
| Acetophenone SCHEMBL16114519 | 0.69 | SMN1; SMN2 (0.46) | LMNAKMT2ASMN1; SMN2TSHRALDH1A1 | |
| Niacin SCHEMBL28944221 | 0.69 | ALDH1A1 (0.68) | LMNAKMT2AHCAR2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105968114-B | A kind of coelenterazine analog and the preparation method and application thereof | 山东大学 | 2018-11-09 | — | — | CN | disclosed |