Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142562 | 0.88 | CTSK (0.45) | CTSKCTSSCA12CA14CA1 | |
| SCHEMBL5145936 | 0.88 | CTSK (0.45) | CTSKCTSSCA12CA14CA1 | |
| SCHEMBL15510765 | 0.88 | CTSK (0.45) | CTSKCTSSCA12CA14CA1 | |
| SCHEMBL5145931 | 0.88 | CTSK (0.45) | CTSKCTSSCA12CA14CA1 | |
| SCHEMBL31703912 | 0.88 | CTSK (0.45) | CTSKCTSSCA12CA14CA1 | |
| SCHEMBL15510764 | 0.88 | CTSK (0.45) | CTSKCTSSCA12CA14CA1 | |
| SCHEMBL14039301 | 0.84 | CTSK (0.49) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL2395128 | 0.84 | CTSK (0.49) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL14453090 | 0.84 | CTSK (0.49) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL14038647 | 0.84 | CTSK (0.49) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794422-A | Heterocycle compound as PD-L1 inhibitor | 南京圣和药业股份有限公司 | 2018-11-13 | — | — | CN | disclosed |